Activity of mannose-binding lectin in centenarians

P 144: Sunflower Mannose binding Lectin-Associated Serine Protease Inhibitor-1 (SFMI-1) and -2: Significant Inhibitors of Mannose binding Lectin Pathway which Helps in Multiple Sclerosis Treatment

One of the important parts of innate immunity is complement system that occurs in three different ways; the classic, the alternative and the lectin pathway. The four pattern recognition molecules that have been identified till now are Mannose binding lectin (MBL), a component of lectin pathway, and three ficolins (ficolin1,-2 and -3) which compound to the carbohydrates of the cell surface. MBL ...

Polymorphisms in the Mannose-Binding Lectin Gene are Associated with Defective Mannose-Binding Lectin Functional Activity in Crohn’s Disease Patients

Mannose-binding lectin, together with mannose-associated serine proteases, activates the lectin pathway of the complement system and subsequent inflammatory mechanisms. An association between mannose-binding lectin deficiency and anti-Saccharomyces cerevisiae antibody levels is observed in Crohn's disease and this deficiency is frequently associated with a severe Crohn's disease phenotype. In t...

Mannose-Binding Lectin-Deficient Mice

mannose-binding lectin mediated complement pathway in autoimmune neurological disorders

multiple sclerosis (ms) is a complex, demyelinating disease of the central nervous system (cns) with variable phenotypic presentations, while guillain-barre syndrome (gbs) is the prototypic acute inflammatory disorder that affects the peripheral nervous system. myasthenia gravis (mg) is a t cell dependent and antibody mediated autoimmune disease. although it has been shown that complement plays...

بررسی سطح سرمی C–Reactive Protein Mannoseو Mannose–Binding Lectin در افراد مبتلا به درماتوفیتوزیس

Background: Interleukin8 (IL-8) realized from keratinocytes in the presence of dermatophytic antigens causesinduction of acute responses in dermatophyte infection and subsequently production of acute phaseproteins occurs in hepatocytes. C–reactive protein (CRP) and Mannose–binding lectin (MBL) areacute phase proteins. Since few researches in the case of acute phase proteins in dermatophyticinfe...